MOCA-B和MES量表对遗忘型轻度认知功能障碍识别的对比研究

A comparative study on the identification of amnestic mild cognitive impairment with MOCA-B and MES scales

目的:本研究旨在比较在记忆门诊中,MOCA-B和MES量表对遗忘性轻度认知功能障碍(Amnesia mild cognitive impairment,aMCI)识别的敏感性和特异性。方法:纳入在记忆门诊以记忆力下降为主诉的68例患者,均完成MMSE、MOCA-B、MES量表及全套神经心理测验评估,以全套神经心理测验作为诊断aMCI的标准,并以此来比较MOCA-B与MES量表对aMCI识别的敏感性和特异性。结果:根据全套神经心理测验的结果,aMCI组有48例,正常组有20例,MOCA-B和MES量表识别aMCI的敏感性分别为93.75%和72.92%((P=0.01),特异性分别为75%和85%,差别无统计学意义(P=1.00))。结论:MOCA-B在记忆门诊中识别aMCI的敏感性优于MES量表,特异性比较无明显差别,值得在记忆门诊中推广使用及进一步研究。

Objective:Expect to find the sensitivity and specificity of the Montreal Cognitive Assessment-Basic(MOCA-B)scales and Memory and Executive Screening(MES)scales of Guoqihao versionon Amnestic mild cognitive impairment(aMCI).Methods:Sixty-eight(68)patients with memory decline were recuited in this study and evaluated by neuropsychological tests(NPT),according to aMCI standard of Petersen.Results:The patients were divided into aMCI group(n=48)and normal group(n=20).The sensitivity of MOCA-B and MES were 93.75%and 72.92%respectively(P=0.01),and the specificity of MOCA-B and MES were 75%and 85%respectively(P=1.00).Conclusion:The sensitivity of MOCA-B scale was significantly better than MES on aMCI,and it need to be studied further.