帕金森病与非帕金森病患者围手术期并发症的对比研究

Comparative study of perioperative complications between Parkinson's and non-Parkinson's patients

目的回顾性分析帕金森与非帕金森患者围手术期并发症的发生情况,为帕金森患者的围手术期管理提供依据。方法选取2014年1月—2019年3月在贵州医科大学附属医院行手术治疗的82例患者作为实验组,另取同期该院行手术治疗的164例非帕金森患者作为对照组。比较两组患者临床资料、围手术期并发症发生率等。结果两组临床资料比较,差异无统计学意义(P>0.05)。对照组术后疼痛发生率高于实验组(P<0.05);而实验组术后肺部感染、泌尿系统感染及谵妄发生率较对照组升高(P<0.05)。两组术后切口感染、胃肠道反应、呼吸功能不全、心律失常及心功能不全等并发症发生率比较,差异无统计学意义(P>0.05)。结论帕金森病患者围手术期更容易发生肺部感染、泌尿系统感染及术后谵妄,但相较于非帕金森病患者术后疼痛的发生率降低。

Objective To retrospectively analyze the incidence of perioperative complications between Parkinson's and non-Parkinson's patients,and to provide the basis of the perioperative management of Parkinson's patients.Method The basic information of Parkinson's patients who accepted surgical treatment in our hospital from January 2014 to March 2019 was selected.According to 1:2 matched case study design,the basic information of non-Parkinson's disease patients who accepted surgical treatment during the same period was randomly selected as contrasting data to find out the use rate of postoperative analgesia pump and the incidence of perioperative complications from the data.Result The basic information and the use rate of postoperative analgesia pump have no significance on statistics between two groups(P>0.05).The incidence of postoperative pain in the control group is higher than in Parkinson's disease group(P<0.05).Compared with the control group,the postoperative pulmonary infection,urinary tract infection,and the incidence of delirium is higher in Parkinson's disease group(P<0.05).Wound infection,gastro-intestinal reactions,respiratory insufficiency,arrhythmia and cardiac insufficiency have no significance on statistics between two groups(P>0.05).Conclusions Parkinson's patients are easily to encounter pulmonary infection,urinary tract infection,and postoperative delirium,but the incidence of postoperative pain in Parkinson's patients is lower than in the control group.