^(18)F-FDG PET/CT显像在胃癌分期鉴别及预后评估中的价值研究

Research on the value of ^(18)F-FDG PET/CT imaging in the staging identification and prognostic assessment of gastric carcinoma

目的:探讨^(18)F-FDGPET/CT显像在胃癌分期鉴别及预后评估中的临床价值。方法:选取医院收治的53例胃癌患者,均行CT增强和^(18)F-FDGPET/CT显像检查,将CT图像资料纳入对照组,^(18)F-FDGPET/CT显像资料纳入观察组。以病理组织学结果为金标准,对比两组显像方法对胃癌分期鉴别和预后评估的准确率,采用卡方检验进行组间差异性比较。结果:临床病理组织学检查结果显示,53例患者中胃癌Ⅰ期、Ⅱ期、Ⅲ期、Ⅳ期分别为5例(占9.43%)、12例(占22.64%)、20例(占37.74%)和16例(占30.19%)。对照组和观察组对胃癌分期的诊断准确率分别为47.17%(25/53)和71.70%(38/53),组间差异有统计学意义(x^(2)=6.613,P<0.05);对照组和观察组对胃癌术后复发的诊断准确率分别为81.13%(43/53)和94.34%(50/53),组间差异有统计学意义(x^(2)=4.296,P<0.05);对照组和观察组对胃癌患者肿瘤转移的诊断准确率分别为66.04%(35/53)和90.57%(48/53),组间差异有统计学意义(x^(2)=9.384,P<0.05)。结论:^(18)F-FDGPET/CT能够较准确地检测胃癌病灶浸润胃壁深度和识别胃周淋巴结转移程度,并对其他器官组织的转移情况诊断效果好,在胃癌的诊疗中表现出较高的临床价值。

Objective:To investigate the clinical application value of ^(18)F-FDG PET/CT imaging in the staging identification and prognostic assessment of gastric carcinoma.Methods:A retrospective analysis was performed on 53 patients with gastric carcinoma who admitted to the hospital.And they underwent the examinations of CT enhancement and ^(18)F-FDG PET/CT imaging,and the CT images data were included in control group and the 18 F-FDG PET/CT imaging data were included in observation group.Histopathological results were used as diagnostic golden standard to compare the accuracy of two imaging methods on staging identification and prognosis assessment of gastric carcinoma.Chi-square test was used to compare the difference of that between the two groups.Results:The results of clinically histopathologic examination indicated that the I stage,II stage,III stage and IV stage of 53 patients with gastric carcinoma were 5 cases(9.43%),12 cases(22.64%),20 cases(37.74%)and 16 cases(30.19%),respectively.The diagnostic accuracies of control group and observation group were 47.17%(25/53)and 71.70%(38/53),respectively,and the difference of that between the two groups was statistically significant(x^(2)=6.613,P<0.05).The diagnostic accuracies of control group and observation group on postoperative recurrence of gastric carcinoma were 81.13%(43/53)and 94.34%(50/53),respectively,and the difference of that between two groups was statistically significant(x^(2)=4.296,P<0.05).The diagnostic accuracies of control group and observation group on the tumor metastasis of patients with gastric carcinoma were 66.04%(35/53)and 90.57%(48/53),and the difference of that between two groups was statistically significant(x^(2)=9.384,P<0.05).Conclusion:18 F-FDG PET/CT can more accurately detect the infiltration depth of gastric carcinoma lesions in gastric wall and identify the metastasis degree of perigastric lymph node,and it has a favorable diagnostic effect of the metastasis in other organs and tissues.It shows higher clinical value in the diagnosis and treatment of gastric carcinoma.