以未分化结缔组织病为首发临床表现的黑热病1例

A case of kala-azar with undifferentiated connective tissue disease as the first clinical manifestation

黑热病也称为内脏利什曼病,主要是由杜氏利什曼原虫感染引起,经白蛉叮咬传播的慢性地方性传染病。由于黑热病临床表现多样,鉴别比较困难,需要特殊的诊断方法才能确定病原。除了典型临床表现,黑热病患者可能有自身免疫性指标异常或类似血液系统疾病症状等,很容易误诊。本文报道1例以未分化结缔组织病为首发临床表现的特殊黑热病病例,分析其临床特点和诊治过程,总结临床经验,旨在增强临床医师对黑热病的认识,提高诊治水平。

Kala-azar,also known as visceral leishmaniasis,is a chronic endemic disease caused by Leishmania donovani infection and transmitted by the bite of sandflies.Due to the variety of clinical manifestations of kala-azar,it is difficult to identify the pathogen,and special diagnostic methods are needed.In addition to the typical clinical manifestations,patients with kala-azar may have abnormal autoimmune indexes or similar symptoms of blood system diseases,which are easy to be misdiagnosed.This paper reports a case of special kala-azar with undifferentiated connective tissue disease as the first clinical manifestation,analyzes its clinical characteristics,diagnosis and treatment process,and summarizes clinical experience,so as to enhance clinicians'understanding of kala-azar and improve the level of diagnosis and treatment.