小柴胡汤合旋覆花汤联合小剂量甲巯咪唑治疗甲状腺功能亢进临床探讨

The exploration on treating hyperthyreosis with the Xiaochaihu decoction plus the Xuanfuhua decoction and low-dose methimazole

目的:探析对甲状腺功能亢进患者应用小柴胡汤合旋覆花汤联合小剂量甲巯咪唑治疗的效果。方法:将我院2016年3月-2020年3月门诊诊治的甲状腺功能亢进患者154例分成两组,分组方法为随机数字表法,对照组77例,实验组77例。对照组予常规剂量甲巯咪唑口服,实验组予小柴胡汤合旋覆花汤联合小剂量甲巯咪唑,分析比较两组治疗效果、甲状腺激素水平、不良反应发生率。结果:实验组总有效率较对照组高,组间差异显著(P<0.05)。两组甲状腺激素的差异显著(P<0.05)。实验组不良反应发生率与对照组比较,组间差异不显著(P>0.05)。结论:对甲状腺功能亢进患者应用小柴胡汤合旋覆花汤联合小剂量甲巯咪唑治疗的效果更加确切,不仅可以有效调节甲状腺激素水平,还不会明显增加不良反应的发生,值得临床借鉴应用。

Objective:To explore the effect of the Xiaochaihu decoction(小柴胡汤)plus the Xuanfuhua decoction(旋覆花汤)and low-dose methimazole on hyperthyroidism.Methods:154 cases were divided into two groups,77 cases in each.The control group was given conventional dose methimazole,and the experimental group was given the Xiaochaihu decoction,the Xuanfuhua decoction with low-dose methimazole.Results:The total efficiency in the experimental group was higher than the control group(P<0.05).There was a significant difference in thyroid hormone between the two groups(P<0.05).The incidence of adverse reactions was not significantly different between the groups(P>0.05).Conclusion:The Xiaochaihu decoction plus the Xuanfuhua decoction and low-dose methimazole on hyperthyroidism is more accurate.It can not only effectively regulate thyroid hormone levels,but also does not significantly increase adverse reactions.It is worthy of clinical application.