加味二仙汤联合回忆疗法对老年性抑郁症女性单胺类神经递质的影响

The effects of the Erxian decoction plus reminiscence therapy on monoamine neurotransmitters of elderly female patients with depression

目的:研究观察加味二仙汤联合回忆疗法对老年性抑郁症女性单胺类神经递质的影响。方法:选择60例老年性抑郁症患者,随机均分成对照组、观察组。对照组予黛力新治疗;观察组予加味二仙汤联合回忆疗法治疗。观察两组的临床疗效。结果:观察组治疗后汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)评分、蒙哥马利抑郁量表(Montgomery Depression Scale,MADRS)评分、老年抑郁量表(Geriatric Depression Scale,GDS)评分低于对照组,5-羟色胺(5-hydroxytryptamine,5-HT)、去甲肾上腺素(Norepinephrine,NE)以及多巴胺(Dopamine,DA)水平高于对照组(P<0.05)。观察组治疗有效率高于对照组(P<0.05)。结论:加味二仙汤联合回忆疗法治疗老年性抑郁症,疗效确切。

Objective:To study and observe the effects of the Erxian decoction(二仙汤)plus reminiscence therapy on monoamine neurotransmitters of elderly female patients with depression.Methods:60 cases were selected and randomly divided into the control group and the observation group.The control group was treated with deanxit.The observation group was treated with the Erxian decoction plus reminiscence therapy.Results:After treatment,HAMD scores,MADRS scores and GDS scores in the observation group were lower than the control group.The 5-HT,NE and DA levels in the observation group were higher than those in the control group(P<0.05).The total efficiency in the observation group was higher than the control group(P<0.05).Conclusion:The Erxian decoction plus reminiscence therapy is effective on senile depression.