摘要
目的探讨肾移植术后感染的发生率、病原菌谱及其危险因素。方法回顾性研究2017年1月至2019年8月于某三级甲等医院成功进行肾移植手术的315例受者临床资料,分析其术后感染发生率、相关病原菌分布特点以及明确影响肾移植受者术后感染的相关因素。结果共144例(45.71%)肾移植受者术后发生感染,且一年内高发(90例,62.50%);病原菌检出共65株,以卡式肺孢子菌感染(14例,21.54%)多见;肺部(79例,54.48%)为主要感染部位。术后住院时间≥15 d是肾移植术后感染发生的危险因素(P<0.001),术后预防性应用更昔洛韦或复方磺胺甲噁唑是其保护因素。结论肾移植术后感染发生率较高,临床医务人员应采取针对性措施进行有效防治,改善患者预后。
Objective To explore the incidence,pathogenic bacteria,related factors of secondary infections after kidney transplantation.Methods The clinical data of 315 recipients who underwent successful allograft kidney transplantation in a tertiary hospital from January 2017 to August 2019 were retrospectively analyzed,with a focus on the incidence of postoperative infection,distribution of related pathogens and the relevant factors affecting the postoperative infection of kidney transplant recipients.Results A total of 144(45.71%)kidney transplant recipients developed postoperative infections and had a high incidence within one year(90,62.50%).A total of 65 pathogenic bacteria were detected,more common with Pneumocystis carinii infection(14,21.54%).The lung(79,54.48%)was the main infection site.The length of hospital stay over 15 days was a risk factor for infection after kidney transplantation,and ganciclovir or SMZ was a protective factor after surgery.Conclusion The incidence of infection after kidney transplantation is very high,and clinical medical staff should take targeted measures to effectively improve the prognosis.
作者
贺雪梅
储爱琴
王玉
张海玲
张言武
司圣波
He Xuemei;Chu Aiqin;Wang Yu;Zhang Hailing;Zhang Yanwu;Si Shengbo(Department of Nursing,the First Affiliated Hospital of University of Science and Technology of China,Hefei 230001,China;不详)
出处
《中国临床保健杂志》
CAS
2021年第1期121-124,共4页
Chinese Journal of Clinical Healthcare
基金
国家临床重点专科建设项目(国卫办医函〔2018〕292号)。
关键词
肾移植
手术后并发症
回顾性研究
感染
Kidney transplantation
Postoperative complications
Retrospective studies
Infections