2008—2017年京籍宫颈癌979例分析

Analysis of 979 cervical cancer patients in Beijing from 2008 to 2017

目的分析北京市开展两癌筛查后本院2008—2017年10年间收治的京籍宫颈癌病例临床病理特点。方法收集2008年1月至2017年12月本院收治的京籍宫颈癌患者979例为研究对象。采用回顾性分析方法,从年龄、临床分期、组织病理学类型等方面分析这些京籍宫颈癌病例的特点。结果979例京籍宫颈癌患者年龄主要集中在35~64岁,占84.8%。临床分期中早期宫颈癌(Ⅰ-ⅡA)所占比例为56.4%,中晚期宫颈癌(ⅡB-Ⅳ)所占比例为43.6%。其中≤34岁组和35~64岁组以早期宫颈癌为主,所占比例分别为70.1%和57.9%;而≥65岁组则以中晚期宫颈癌居多,所占比例为76.4%。组织病理学类型以鳞癌为主,所占比例高达91.3%。结论北京市实行宫颈癌免费筛查后10年间,京籍宫颈癌患者年龄集中在免费筛查的年龄段35~64岁,因此应加强北京市宫颈癌筛查的宣传,提高人群筛查率。针对年轻和中年的宫颈癌患者确诊时多为早期,而老年妇女宫颈癌患者确诊时多为中晚期的问题,应加强老年妇女宫颈癌筛查和宫颈癌防治知识的教育。

Objective To explore the clinicopathological characteristics of cervical cancer(CC)among local patients admitted to Beijing Obstetrics and Gynecology Hospital,during a 10-year's period from 2008 to 2017.Methods From January 2008 to December 2017,979 CC patients admitted to Beijing Obstetrics and Gynecology Hospital were collected.A retrospective analysis method was used to analyze the characteristics of those CC cases,including onset age,clinical stage,and histopathological type.Results The onset age among 84.8% patients was between 35 and 64 years old.According to clinical stage,the proportion of early CC(Ⅰ-ⅡA)was 56.4%,and that of advanced CC(ⅡB-Ⅳ)was 43.6%.For early CC,most of them were identified among the subgroup of ≤34 or 35-64 years old,accounting for 70.1% and 57.9% of all analyzed early CC cases,respectively.While,for the cases of middle or late stage,most of them(i.e.,76.4%)were above 65 years old.According to the histopathological type,91.3% was squamous cell carcinoma.Conclusion During the first 10 years of free CC screening in Beijing,the diagnosed age of cancer onset was remained between 35 and 64 years old,which suggested that the CC screening in Beijing should be strengthened to increase the rate of population coverage.For young-or middle-aged patients,most CC cases were diagnosed at their early stage;for elderly women,the diagnoses were mostly possible at their middle and late stages.The comparison suggests that the education of screening,prevention,treatment for CC should be strengthened among elderly women.