脑电双频指数监测在妇科腹腔镜手术麻醉中的应用效果

Anesthetic monitoring of bispectral index during gynecological laparoscopy

目的观察脑电双频指数(BIS)监测在妇科腹腔镜手术麻醉中应用价值。方法80例行妇科腹腔镜手术全麻患者随机分为BIS组和常规组,比较两组平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO2)和血清肾上腺素、β-内啡肽、皮质醇水平、以及丙泊酚/瑞芬太尼用量、苏醒时间、不良反应。结果BIS组平均动脉压、心率高于常规组(P<0.05),而丙泊酚用量、苏醒时间及肾上腺素、β-内啡肽、皮质醇水平低于常规组(P<0.05)。两组瑞芬太尼用量、不良反应差异无统计学意义(P>0.05)。结论妇科腹腔镜手术全麻中应用BIS监测,有利于维持血流动力学、合理麻醉深度及减轻应激反应。

Objective To observe the anesthetic monitoring of bispectral index(BIS)during gynecological laparoscopy.Methods Eighty patients underwent gynecological laparoscopy with general anesthesia were randomized to BIS and routine groups.Mean arterial pressure(MAP),heart rate(HR),blood oxygen saturation(SpO_(2)),serum epinephrine,β-endorphin and cortisol levels,propofol and remifentanil dosage,awakening time,and adverse reactions were compared between two groups.Results Compared with routine group,MAP and HR were higher(P<0.05),while serum epinephrine,β-endorphin and cortisol levels,propofol dosage,and awakening time were lower(P<0.05)in BIS group.There was no significant difference in remifentanil dosage and adverse reactions between two groups(P>0.05).Conclusion BIS monitoring is helpful to maintain the hemodynamics and reasonable anesthetic depth,and alleviate the stress response during general anesthesia of gynecological laparoscopy.