儿童急性呼吸道感染非典型病原体病原学检测与临床研究

Etiological Detection and Clinical Study of Atypical Pathogens in Children with Acute Respiratory Infection

目的研究儿童急性呼吸道非典型病原体感染特征,为防控诊疗提供依据。方法收集2016年9月-2019年8月期间住院患儿1 040例,检测肺炎支原体(Mycoplasma pneumoniae,MP)和肺炎衣原体(Chlamydia pneumoniae,CP),分析感染情况。结果检出病原体452株,阳性率43.46%,冬春季检出率高于夏秋季(χ^(2)=9.305,P=0.002),5~14岁组,MP检出最多。MP(肺炎)平均住院时间最长和住院费用最高。结论儿童急性呼吸道感染非典型性病原体检出率因季节、年龄不同存在差异,造成的疾病负担也不同。

Objective To study the characteristics of atypical pathogens in children with acute respiratory infection, and to provide basis for prevention and control and reasonable clinical diagnosis and treatment. Methods The 1040 hospitalized children from September 2016 to August 2019 were collected. The Mycoplasma pneumoniae(MP) and Chlamydia pneumoniae(CP) were detected to analyze the infection situation. Results A total of 452 strains of atypical pathogens were detected, with a positive rate of 43.46%,.The positive rate in winter and spring was higher than that in summer and autumn(χ^(2)=9.305, P=0.002), and the detection rate of MP was highest in 5~14 years old group. The average hospitalization time of MP(pneumonia) was the longest, and the average hospitalization cost was the highest. Conclusion Atypical pathogens of acute respiratory infection in children are mainly MP and CP, and their detection rate varies with seasons and ages, and the disease burden of infected children is also different.