柴胡疏肝散联合孟鲁司特纳治疗胸闷变异性哮喘21例临床观察

Chaihushugansan Combined with Montelukastner in the Treatment of 21 Patients with Chest Tightness Variant Asthma

目的:观察柴胡疏肝散联合孟鲁司特纳治疗胸闷变异性哮喘肝郁气滞证的临床疗效。方法:将42例胸闷变异性哮喘肝郁气滞患者按随机数字法分为对照组和治疗组各21例,对照组口服孟鲁司特纳,治疗组予以孟鲁司特纳和柴胡疏肝散联合治疗。结果:治疗后两组肺功能指标FEV1/FVC、PEF(%)均得到改善,差异具有统计学意义(P<0.05);但与对照组相比,治疗组改善率明显高于对照组,差异具有统计学意义(P<0.05);对照组总有效率为76.2%,治疗组为90.5%,治疗组明显优于对照组(P<0.05)。结论:柴胡疏肝散联合孟鲁司特纳治疗胸闷变异性哮喘肝郁气滞证能有效缓解患者症状,改善肺功能,值得临床推广。

Objective To observe the clinical efficacy of Chaihu Shugan Powder in treating chest tightness variant asthma.Methods According to random number method,42 Patients with chest tightness variant asthma were divided into treatment grou P and control grou P,21 cases each.The control grou P received oral montelukast,and the treatment grou P received combined treatment of montelukast and Chaihu Shugan Powder.Results After treatment,the lung function indexes FEV1/FVC and PEF(%)of the two grou Ps were im Proved,the difference was statistically significant(P<0.05);but com Pared with the control grou P,the im Provement rate of the treatment grou P was significantly higher than that of the control grou P,The difference was significant(P<0.05);after adding Chaihu Shugan Powder,the total effective rate of the control grou P was 76.2%,and that of the treatment grou P was 90.5%.The treatment grou P was significantly better than the control grou P(P<0.05).Conclusion Chaihu Shugan Powder can effectively im Prove the sym Ptoms of Patients with chest tightness variant asthma and liver qi stagnation syndrome,and it deserves clinical attention.