超重人群腹部脂肪含量与腰椎骨密度相关性研究

Correlation Between Abdominal Fat and Lumbar Vertebral Bone Mineral Density in Overweight People

目的:探究超重人群腰椎骨密度(BMD)与年龄、身高、体重和腹部脂肪面积的关系。方法:以来我院进行定量CT(QCT)体检的人员作为研究对象,并分为正常组和超重/肥胖组,分别测量每位研究对象的腰椎(L1、L2、L3)BMD值。分别测量计算出腰椎横断位中心层面腹部总脂肪面积、内脏脂肪面积、皮下脂肪面积。结果:正常组年龄与腰椎BMD呈显著负相关(P<0.05);正常组、超重/肥胖组内脏脂肪面积与腰椎BMD呈显著负相关(P<0.05)。身高、体重、腹部皮下脂肪面积和总脂肪面积与腰椎BMD无显著相关性(P>0.05)。结论:随着年龄增长,腰椎BMD逐渐降低。对于超重患者,内脏脂肪的增多与腰椎BMD呈显著负相关关系。这对骨质疏松的发病机制探究和骨质疏松的预防有一-定指导意义。

Purpose:To investigate the correlation between lumbar bone mineral density(BMD)and age,height,weight and abdominal fat area in overweight and obese people.Methods:People who underwent physical examination in our hospital were enrolled and divided into normal weight group and overweight/obese group.The BMD of lumbar spine(L1,L2,L3)and various physical composition parameters were measured by quantitative CT(QCT)respectively.The total adipose tissue,subcutaneous adipose tissue,and visceral adipose tissue were measured at the levels of L1,L2,and L3.Results:The age of normal group showed a significantly negative correlation with lumbar BMD(P<0.05).The visceral adipose tissue of normal group and overweight/obese group showed a significantly negative correlation with lumbar BMD(P<0.05).Height,weight,subcutaneous adipose tissue and total adipose tissue had no significant correlation with lumbar BMD(P>0.05).Conclusion:With the increase of visceral adipose tissue,the lumbar BMD at the central level ofL1,L2,and L3 gradually decreased.