世界过敏组织关于IgE介导过敏反应的诊断及过敏反应其他相关检测方法立场文件解读(二)——体外检测

Interpretation of position paper from the World Allergy Organization for IgE allergy diagnostics and other relevant tests in allergy(part two:in vitro tests)

2020年世界过敏组织发布了关于免疫球蛋白E (IgE)介导的过敏反应诊断及检测方法的立场文件,对最常用的体内和体外检测进行了新的全面评估。本文就体外检测部分进行重点解读,主要介绍血清总IgE、过敏原特异性IgE检测、嗜碱性粒细胞活化试验3种试验方法,旨在帮助医务工作者更好地理解立场文件,进一步了解过敏反应相关的检测方法,以做出准确的诊断,制定出最佳的治疗方案。

In 2020,the World Allergy Organization released a position paper on the immunoglobulin E(IgE)allergy diagnostics and tests,which provided a thorough and updated appraisal of the most frequently used diagnostic tests,both in vivo and in vitro.This article focused on the interpretation of in vitro tests,mainly introduced three test methods of serum total IgE,allergen specific IgE detection and basophil activation test,aiming to help medical workers better understand the position paper,and further understand the diagnosis methods,so as to make accurate diagnosis and formulate the optimal treatment.