溶栓疗法结合脑心通胶囊治疗急性肺栓塞临床观察

目的:观察溶栓疗法结合脑心通胶囊治疗急性肺栓塞的效果。方法:96例用简单随机分组法分为观察组和对照组各48例,两组均用溶栓疗法治疗,观察组加用脑心通胶囊治疗。结果:总有效率观察组高于对照组(P<0.05)。两组1s用力呼气容积(FEV1)、1s用力呼气容积/正常预计值(FEV1%)、用力肺活量/正常预计值(FVC%)水平均高于治疗前(P<0.05),且观察组的FEV1、FEV1%、FVC%水平均高于对照组(P<0.05)。两组凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)水平均高于治疗前(P<0.05),且观察组PT、APTT、TT水平均高于对照组(P<0.05)。随访6个月,终点事件发生率观察组低于对照组(P<0.05)。结论:溶栓疗法结合脑心通胶囊治疗急性肺栓塞疗效较好。

Objective:To observe the effect of thrombolytic therapy combined with Naoxintong Capsule in the treatment of acute pulmonary embolism.Methods:Ninety-six cases were divided into the observation group and the control group,with 48 cases in each group,according to simple random grouping.Both groups were treated with thrombolytic therapy,and the observation group were treated with Naoxintong Capsules in addition.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).The two groups’1 s forced expiratory volume(FEV1),1 s forced expiratory volume/normal predicted value(FEV1%),forced vital capacity/normal predicted value(FVC%)levels after treatment were higher than those before treatment(P<0.05),and the levels of FEV1,FEV1%and FVC%of the observation group were higher than those of the control group(P<0.05).The levels of prothrombin time(PT),activated partial thromboplastin time(APTT),and thrombin time(TT)in the two groups after treatment were higher than those before treatment(P<0.05),and the PT,APTT,and TT levels in the observation group were higher than the control group(P<0.05).After 6 months of follow-up,the end-point event rate of the observation group was lower than that of the control group(P<0.05).Conclusion:Thrombolytic therapy combined with Naoxintong Capsule is effective in treating acute pulmonary embolism.