摘要
肺缺血/再灌注损伤(lung ischemia/reperfusion injury, LIRI)是缺血肺组织恢复血供后,组织损伤反而加重的现象。LIRI可致肺动脉高压、低氧血症等,甚至造成呼吸衰竭。迄今为止有关LIRI方面的研究很多,文章回顾了国内外有关LIRI方面的研究,简述了LIRI的机制及相应的肺保护策略,总结了当前LIRI防治方面的研究进展,以期为临床提供参考。
Lung ischemia/reperfusion injury(LIRI)is a phenomenon that tissue damage is aggravated after the blood supply of ischemic lung tissue is restored.LIRI can cause pulmonary hypertension,hypoxemia,and even respiratory failure.Up to now,there have been many types of research on LIRI.This paper reviews the researches on LIRI at home and abroad,briefly describes the mechanism of LIRI and the corresponding lung protection strategies,summarizes the current research progress in the prevention and treatment of LIRI to provide a reference for clinical practice.
作者
闫学美
郎堡
袁方
兰楠楠
Yan Xuemei;Lang Bao;Yuan Fang;Lan Nannan(School of Anesthesiology,Weifang Medical University,Weifang 261042,China;Department of Anesthesiology,Weifang People's Hospital,Weifang 261041,China)
出处
《国际麻醉学与复苏杂志》
CAS
2021年第3期306-311,共6页
International Journal of Anesthesiology and Resuscitation
关键词
肺
缺血/再灌注损伤
肺保护策略
Lung
Ischemia/reperfusion injury
Lung protection strategy
