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基于微流血型检测卡的血型判读试验 被引量:1

Blood type interpretation test based on microfluidic blood group detection card
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摘要 为验证微流血型检测卡可实现血型检验工作,搭建自动化血型检测硬件平台,将微流血型检测卡作为反应容器,充分反应后把原始图像分割为单通道图像,直接取用R通道像素值进行灰度化,再使用Sobel算子提取边缘信息,最后用图像信息熵的方法得到图像信源的平均信息量,即可获得血型判读结果。实验结果表明:数字图像处理能够快速有效地判读血型信息,并通过重复性测试得知适于大样本检测,所以使用微流血型检测卡能够完全满足全自动血型分析仪的血型判读要求。 In oder to verify that the micro-bleed blood type detection card can achieve blood type testing,an automated blood type detection hardware platform is built,the microfluidic blood group detection card is used as a reaction container,the original image is divided into single-channel images after full reaction.The R channel pixel value is directly used for grayscale,and then the Sobel operator is used to extract edge information.Finally,the method of image information entropy is used to obtain the average information amount of the image source,and the result of blood group interpretation is obtained.The experimental results show that the blood type information can be quickly and effectively interpreted through digital image processing,and it is known that it is suitable for large sample detection through repetitive testing.Therefore,the use of the microfluidic blood group detection card can fully meet the blood type interpretation requirements of the automatic blood type analyzer.
作者 刘怀宾 朱继伟 石鑫 杨晋 李洪博 LIU Huaibin;ZHU Jiwei;SHI Xin;YANG Jin;LI Hongbo;无(Changchun Institute of Optics,Fine Mechanics and Physics,Chinese Academy of Sciences,Changchun 130033,China;University of Chinese Academy of Sciences,Beijing 100049,China;Jilin Guoke Medical Technology Development Co.,Ltd.,Changchun 130000,China;Changchun Zhongke Science and Technology Co.,Ltd.,Changchun 130000,China)
出处 《中国测试》 CAS 北大核心 2021年第4期44-48,共5页 China Measurement & Test
基金 吉林省科技发展计划项目(20200403009SF)。
关键词 微流血型检测卡 溯源 血型判读 SOBEL算子 图像信息熵 数字图像处理 microfluidic blood group detection card traceability blood type interpretation Sobel operator image information entropy digital image processing
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