摘要
Chiral ligand conjugated transition metal oxide nanoparticles(NPs) are a promising platform for chiral recognition, biochemical sensing, and chiroptics. Herein, we present chirality-based strategy for effective sensing of mercury ions via ligand-induced chirality derived from metal-to-ligand charge transfer(MLCT) effects. The ligand competition effect between molybdenum and heavy metal ions such as mercury is designated to be essential for MLCT chirality. With this know-how, mercury ions, which have a larger stability constant(Kf) than molybdenum, can be selectively identified and quantified with a limit of detection(LOD) of 0.08 and 0.12 nmol/L for D-cysteine and L-cysteine(Cys) capped Mo O2 NPs. Such chiral chemical sensing nanosystems would be an ideal prototype for biochemical sensing with a significant impact on the field of biosensing, biological systems,and water research-based nanotoxicology.
基金
Science,Technology and Innovation Commission of Shenzhen Municipality(JCYJ20180305180553701,KQTD2015071710313656)
Guangdong Basic and Applied Basic Research Foundation(2019A1515012094)
Natural Science Foundation of Hubei Province(2020CFB200)
Shenzhen Fundamental Research Foundation(JCYJ20180508162801893)
National Natural Science Foundation of China(21805234,22075240)
Guangdong Introducing Innovative and Enterpreneurial Teams(2019ZT08L101)
Shenzhen Institute of Artificial Intelligence and Robotics for Society(AIRS)。