儿童对新型冠状病毒易患机制的初步探讨

Discussion on the 2019 Novel Coronavirus susceptible mechanism in children

儿童是感染性疾病的易患人群,但我国儿童感染新型冠状病毒(2019 Novel Coronavirus,2019-nCoV)例数占比相对较小,重症比例更低。这可能与2019-nCoV细胞受体在儿童体内结合力较低或者诱导的细胞内反应较低、儿童免疫系统发育不成熟、儿童发生淋巴细胞消耗和炎症因子风暴较少见以及中国严格的防控措施使儿童感染机会相对较少有关。

Although children are susceptible to infectious diseases,the cases of children infected with 2019 Novel Coronavirus(2019-nCoV)is relatively low,and the proportion of severe illnesses is even lower.The reason is that the 2019-nCoV cell receptor has low binding capacity in children or the induced intracellular response is low,children’s immune system is immature,lymphocyte depletion and inflammatory factor storms are rare in children,and China′s strict prevention and control measures have kept children away from 2019-nCoV.