尿激酶联合红外线治疗仪在血液透析患者动静脉内瘘溶栓中的护理研究

Nursing study of urokinase combined with infrared therapy instrument in thrombolysis of arteriovenous internal fistula in hemodialysis patients

目的:探讨尿激酶联合红外线治疗仪在血液透析患者动静脉内瘘溶栓中的护理效果。方法:选取进行维持性血液透析且形成动静脉内瘘血栓的患者15例,注射尿激酶联合红外线治疗仪进行治疗,并给予尿激酶溶栓护理;观察临床效果。结果:15例患者中,成功14例(93.3%);随访5个月,治疗后第1、2、3、4、5个月的通畅率分别为86.7%、73.3%、66.7%、66.7%、60.0%;治疗后患者D-二聚体(D-D)、纤维蛋白原(FIB)、凝血酶原时间(PT)、活化部分凝血活酶时间(APPT)、尿蛋白及总胆红素等指标水平均明显下降,与治疗前比较,差异有统计学意义(P<0.05)。结论:注射尿激酶联合使用红外线治疗,对血液透析患者动静脉内瘘溶栓的治疗效果显著,安全性较高。

Objective:To explore the nursing effect of urokinase combined with infrared therapy instrument in thrombolysis of arteriovenous internal fistula in hemodialysis patients.Methods:15 patients with arteriovenous internal fistula thrombosis who underwent maintenance hemodialysis were selected.They were treated with urokinase combined with infrared therapy instrument,and given urokinase thrombolysis nursing.Observe the clinical effect.Results:Of the 15 patients,14(93.3%)cases were successful.The patency rates at the 1,2,3,4 and 5 months after treatment were 86.7%,73.3%,66.7%,66.7%and 60.0%,respectively.After treatment,the levels of D-dimer(D-D),fibrinogen(FIB),prothrombin time(PT),activated partial thromboplastin time(APPT),urinary protein and total bilirubin decreased significantly,compared with those before treatment,with the differences were statistically significant(P<0.05).Conclusion:Urokinase injection combined with infrared therapy has a significant effect on thrombolysis of arteriovenous internal fistula in hemodialysis patients with high safety.