鼻内镜手术联合糖皮质激素治疗慢性鼻窦炎患者的临床效果分析

Analysis on the clinical efficacy of nasal endoscopic surgery combined with glucocorticoid in the treatment of patients with chronic sinusitis

目的探讨鼻内镜手术联合糖皮质激素治疗慢性鼻窦炎患者的临床疗效。方法选择我院2018年5月至2020年5月收治的155例慢性鼻窦炎患者,随机分为观察组(n=78)和对照组(n=77)。对照组采用鼻内镜手术治疗,观察组在此基础上联合糖皮质激素治疗。观察比较两组临床疗效、Lund-Kennedy评分及并发症发生情况。结果观察组总有效率为92.31%,高于对照组的80.52%(P<0.05)。治疗后,观察组Lund-Kennedy评分由(6.61±2.02)分下降至(1.41±0.31)分,对照组Lund-Kennedy评分由(6.43±1.71)分下降至(2.69±0.71)分(P<0.05),且观察组Lund-Kennedy评分低于对照组[(1.41±0.31)分vs(2.69±0.71)分],差异有统计学意义(P<0.05)。观察组术后并发症总发生率(7.69%)低于对照组(19.48%),差异有统计学意义(P<0.05)。结论鼻内镜手术联合糖皮质激素治疗慢性鼻窦炎临床疗效显著,可有效缓解临床症状,降低Lund-Kennedy评分及并发症发生率,安全性高。

Objective To investigate the clinical efficacy of nasal endoscopic surgery combined with glucocorticoid in the treatment of patients with chronic sinusitis.Methods A total of 155 patients with chronic sinusitis admitted to our hospital from May 2018 to May 2020 were selected,and they were randomly divided into the observation group(n=78)and the control group(n=77).The control group was treated with nasal endoscopic surgery,while the observation group was treated with glucocorticoid on this basis.The clinical efficacy,Lund-Kennedy score and incidence of complications of the two groups were observed and compared.Results The total efficacy rate of the observation group was 92.31%,higher than 80.52%of the control group(P<0.05).After treatment,the Lund-Kennedy score of the observation group decreased from(6.61±2.02)points to(1.41±0.31)points,while that of the control group decreased from(6.43±1.71)points to(2.69±0.71)points(P<0.05),and Lund-Kennedy score of the observation group was lower than that of the control group([1.41±0.31]points vs[2.69±0.71]points),with statistically significant differences(P<0.05).The total incidence of postoperative complications in the observation group was 7.69%,lower than 19.48%in the control group,with statistically significant difference(P<0.05).Conclusion Nasal endoscopic surgery combined with glucocorticoids is effective in treating chronic sinusitis,which can effectively relieve clinical symptoms and reduce Lund-Kennedy score and incidence of complications,with high safety.