关于特发性膜性肾病中医病因病机的论述

Discussion on the traditional Chinese medicine etiology and pathogenesis of idiopathic membranous nephropathy

膜性肾病(MN)是一类发病类型复杂、病因病机尚未完全明确的一种疾病,分为特发性(IMN)和继发性(SMN),随病情发展可至终末期肾衰竭,其中病因尚未明确的称为IMN。近年来临床研究表明,中医药在用于治疗该疾病时对症状缓解、防治并发症及延缓特发性膜性肾病的发展进程等方面有明显疗效。参考各家文献,大多数医家认为特发性膜性肾病的基本病机是本虚标实,风、湿、热、瘀是在影响疾病发生发展的四大重要病机。在临床指导治疗IMN中从不同临床表现来探讨中医病因病机的研究具有重要意义。

Membranous nephropathy(MN)is a type of disease with complex pathogenesis and unclear etiology and pathogenesis.It is divided into idiopathic membranous nephropathy(IMN)and secondary membranous nephropathy(SMN).With the development of the disease,it can reach end-stage renal failure.The membranous nephropathy with unclear etiology is called IMN.In recent years,clinical studies have shown that traditional Chinese medicine has obvious effects on symptom relief,prevention and treatment of complications,and delaying the development of idiopathic membranous nephropathy when used in the treatment of diseases.With reference to various literature,most physicians believe that the basic pathogenesis of idiopathic membranous nephropathy is the Benxu Biaoshi.Wind,dampness,heat,and blood stasis are the four important pathogenesis that affects the disease's development.The study of the etiology and pathogenesis of TCM from different clinical manifestations is of great significance in clinical guidance and treatment of IMN.