曲克芦丁联合灯盏花素注射液治疗急性脑梗死的疗效观察

Observation of efficacy of troxerutin combined with breviscapine injection in the treatment of acute cerebral infarction

目的探讨曲克芦丁联合灯盏花素注射液治疗急性脑梗死的临床效果。方法60例急性脑梗死患者,随机分为对照组和观察组,各30例。对照组采用灯盏花素注射液治疗,观察组采用曲克芦丁联合灯盏花素注射液治疗。比较两组临床疗效及治疗前后美国国立卫生研究院卒中量表(NIHSS)评分。结果观察组临床治疗总有效率90.00%明显高于对照组的66.67%,差异具有统计学意义(P<0.05)。治疗前,两组NIHSS评分比较差异无统计学意义(P>0.05);治疗后,两组NIHSS评分均显著低于治疗前,且观察组NIHSS评分(3.08±1.21)分低于对照组的(5.15±1.59)分,差异具有统计学意义(P<0.05)。结论曲克芦丁联合灯盏花素注射液治疗急性脑梗死患者疗效显著,可有效改善患者神经功能缺损情况,具有一定的推广价值。

Objective To discuss the clinical effect of troxerutin combined with breviscapine injection in the treatment of acute cerebral infarction.Methods A total of 60 patients with acute cerebral infarction were randomly divided into control group and observation group,with 30 cases in each group.The control group was treated with breviscapine injection,and the observation group was treated with troxerutin combined with breviscapine injection.The clinical efficacy,and National Institutes of Health stroke scale(NIHSS)score before and after treatment were compared between the two groups.Results The total effective rate of the observation group was 90.00%,which was obviously higher than 66.67%of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in NIHSS score between the two groups(P>0.05).After treatment,the NIHSS score of the two groups was significantly lower than that before treatment,and NIHSS score(3.08±1.21)points of the observation group was lower than(5.15±1.59)points of the control group.All the difference was statistically significant(P<0.05).Conclusion Combination of troxerutin and breviscapine injection shows remarkable efficacy in the treatment of patients with acute cerebral infarction,and it can reduce the neurological deficit score of patients.This method has certain clinical application and promotion value.