艺术疗法对乳腺癌患者焦虑和抑郁情绪影响的Meta分析

Art therapy:a meta-analysis of the effect of anxiety and depression in patients with breast cancer

目的评价艺术疗法对改善乳腺癌患者焦虑和抑郁情绪的疗效。方法检索PubMed、Embase、Web of science、Scopus、Cochrane library、Google scholar等外文数据库及中文数据库包括维普数据库、中国生物医学数据库、知网期刊数据库、万方期刊数据库中艺术疗法对乳腺癌患者焦虑和抑郁情绪的随机对照试验,采用偏倚风险评估工具对文献质量进行评价,采用RevMan 5.3进行Meta分析。结果最终共纳入12项随机对照试验研究,共905例乳腺癌患者,其中试验组451例,对照组454例。Meta分析结果显示,艺术疗法可改善乳腺癌患者焦虑情绪[均数差(mean difference,MD)=-7.04,95%CI(-9.50,-4.58),P<0.0001];改善乳腺癌患抑郁情绪[MD=-4.68,95%CI(-7.02,-2.34),P<0.0001]。结论艺术疗法可改善乳腺癌患者焦虑和抑郁情绪。本次研究所纳入样本量有限,后续可继续开展多中心、大样本的高质量研究,为乳腺癌患者实施艺术疗法提供更多循证依据。

Objective To evaluate the effect of art therapy in breast cancer patients who having anxiety and depression.Methods It was a clinical randomised controlled study.Articles about art therapy of anxiety and depression in patients with breast cancer were retrieved from the databases of PubMed,Embase,Webofscience,Scopus,Cochranelibrary,Googlescholar and the Chinese language databases including VIP,Chinese Biomedical,CNKI,and Wanfang.The quality of the retrieved papers was assessed according to the Cochrane Handbook for Systematic Reviews.RevMan 5.3 software was used in meta-analysis.Results A total of 12 clinical randomised controlled studies with 905 breast cancer patients were included in this study,of which 451 patients were in the art therapy group and 454 in the control group.Meta-analysis showed that the anxiety in the art therapy group was significantly lower than that of the control group[MD=-7.040,95%CI(-9.50,-4.58),(P<0.0001)],while the depression in the art therapy group was significantly better than that of the control group[MD=-4.680,95%CI(-7.02,-2.34),(P<0.0001)].Conclusion The art therapy improves the anxiety and depression in patients with breast cancer.