胰岛素泵与利拉鲁肽治疗老年超重2型糖尿病的疗效与安全性

Efficacy and Safety of Liraglutide and Insulin Pump in the Treatment of Elderly Overweight Type 2 Diabetes

目的:探讨胰岛素泵与利拉鲁肽治疗在老年超重2型糖尿病患者中的应用效果。方法:将68例老年超重2型糖尿病患者分为观察组(胰岛素泵)和对照组(利拉鲁肽)各34例,对比其治疗效果。结果:与对照组相比,观察组患者的治疗有效率(94.12%>73.53%)、SF-36评分((78.82±4.24)分>(69.14±5.16)分)相对更高(P<0.05),并发症发生率(8.82%<32.35%)、FBG((6.29±1.05)<(8.04±1.16)mmol/L)、2h PBG((8.74±1.38)<(10.39±1.57)mmol/L)、BMI((23.51±2.04)<(27.75±2.36)kg/m^(2))相对更低(P<0.05)。结论:老年超重2型糖尿病的临床治疗,胰岛素泵治疗在疗效和安全性方面具有显著优势。

Objective:To investigate the effect of insulin pump and Lilarubicin in elderly patients with overweight type 2 diabetes mellitus.Methods:68 elderly patients with overweight type 2 diabetes mellitus were divided into observation group(n=34)and control group(n=34).Results:Compared with the control group,the treatment effective rate(94.12%>73.53%)and SF-36 score[(78.82±4.24)points>(69.14±5.16)points]of the observation group were relatively higher(P<0.05),Complication rate(8.82%<32.35%),FBG[(6.29±1.05)mmol/L<(8.04±1.16)mmol/L],2h PBG[(8.74±1.38)mmol/L<(10.39±1.57)mmol/L],BMI[(23.51±2.04)kg/m^(2)<(27.75±2.36)kg/m^(2)]relatively lower(P<0.05).Conclusion:The clinical treatment and insulin pump therapy of overweight type 2 diabetes mellitus in the elderly have significant advantages in efficacy and safety.