摘要
谷氨酸-组氨酸-赖氨酸(GHK)存在于人血液、唾液、尿液中,具有多种生物学作用。据目前知识所知,这些作用都是对健康有益的。其可促进伤口愈合和组织再生,抗炎、抗氧化,还可增加胶原蛋白、弹力蛋白和糖胺聚糖的合成。目前已经证明GHK可以作为治疗性成分在慢性阻塞性肺疾病和代谢性癌症中应用。本文主要关注GHK在呼吸系统疾病中的应用进展,为进一步实验研究及指导临床奠定基础。
Glycyl-histidyl-lysine(GHK)exists in human blood,saliva and urine,and has various biological functions.According to current knowledge,these effects are beneficial to health.It can promote wound healing and tissue regeneration,have anti-inflammatory and antioxidation,increase the synthesis of collagen,elastin and glycosaminoglycans.It has been proved that GHK can be used as a therapeutic component in treatment of chronic obstructive pulmonary disease and metabolic cancer.This article focuses on the development of GHK in respiratory diseases,laying a foundation for further experimental research and clinical guidance.
作者
王钰
张勤
马文会
刘丽
周晓明
侯刚
Wang Yu;Zhang Qin;Ma Wenhui;Liu Li;Zhou Xiaoming;Hou Gang(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of China Medical University,Shenyang 110001,China)
出处
《国际呼吸杂志》
2021年第6期471-474,共4页
International Journal of Respiration
基金
辽宁省科技厅自然科学基金(2018011494-301)。
