中国各地区妊娠期妇女甲状腺相关激素参考值范围研究进展

Research progress on the reference value range of thyroid related hormone during pregnancy in different regions of China

妊娠期妇女甲状腺疾病的发生与不良的妊娠结局密切相关,严重危害母儿健康。妊娠期妇女甲状腺相关激素水平受多种因素的影响,除了母体内环境变化,还与饮食结构、生活习惯等有关。不同的地理位置、地形地貌也会对妊娠期妇女甲状腺相关激素水平产生一定的影响。内陆城市相比于沿海城市,妊娠期妇女甲状腺相关激素水平相对较低。内陆城市中靠近北方的地区,妊娠期妇女甲状腺相关激素水平相对较高。高原和平原地区的妊娠期妇女甲状腺相关激素水平无明显差别。中国大部分地区基本建立了妊娠各期甲状腺相关激素特异性参考值范围。关注中国不同地区妊娠期妇女甲状腺相关激素值的参考范围有助于我国妊娠期甲状腺疾病的诊治,以减少不良妊娠结局的发生。

The occurrence of thyroid disease during pregnancy is closely related to adverse pregnancy outcomes,which seriously endangers the maternal and children’s health.The levels of thyroid related hormone during pregnancy are affected by many factors,including the changes of internal environment in maternal body,diet structure and living habit.Different geographical location,topography also have a certain impact on the levels of thyroid related hormone during pregnancy.Compared to the coastal cities,the levels of thyroid related hormone during pregnancy in inland city is relatively low.And the levels of thyroid related hormone during pregnancy were relatively high in the areas near the north among the inland cities.There was no significant difference in the levels of thyroid related hormone during pregnancy between plateau and plain areas.In most areas of China,the specific reference value range of thyroid related hormone in different stages of pregnancy has been basically established.Paying attention to the reference range of thyroid related hormone during pregnancy in different regions of China is helpful for the diagnosis and treatment of thyroid diseases during pregnancy,so as to reduce the incidence of adverse pregnancy outcomes.