腹腔镜在早期胃癌治疗中的应用效果

Application Effect of Laparoscopy in the Treatment of Early Gastric Cancer

目的探讨腹腔镜在早期胃癌治疗中的应用效果。方法选取2016年4月~2019年3月我院收治的90例早期胃癌患者作为研究对象,根据手术方式不同分为对照组和实验组,每组45例。对照组采用开腹手术治疗,实验组采用腹腔镜手术治疗,比较两组临床指标、应激指标、术后并发症发生情况及远期营养状况。结果实验组术中出血量少于对照组,手术时间与术后住院时间短于对照组,肛门排气时间、下床活动时间和进食时间早于对照组(P<0.05)。实验组hs-CRP、IL-6与TNF-α水平低于对照组(P<0.05)。实验组并发症总发生率为6.67%,低于对照组的31.11%(P<0.05)。术后1年,实验组血红蛋白、血清白蛋白水平高于对照组,BMI高于术前例数多于对照组(P<0.05);两组血清总蛋白水平比较,差异无统计学意义(P>0.05)。结论与传统开腹手术相比,早期胃癌患者实施腹腔镜手术后创伤小、出血量少、手术及住院时间短、并发症少,有助于促进患者术后恢复,且患者远期健康状况良好。

Objective To explore the effect of laparoscopy in the treatment of early gastric cancer.Methods A total of 90 patients with early gastric cancer admitted to our hospital from April 2016 to March 2019 were selected as the research objects.According to different surgical methods,they were divided into a control group and an experimental group,with 45 cases in each group.The control group was treated with open surgery,and the experimental group was treated with laparoscopic surgery.The clinical indicators,stress indicators,postoperative complications and long-term nutritional status of the two groups were compared.Results The amount of blood loss during operation in the experimental group was less than that in the control group,the operation time and postoperative hospital stay were shorter than those in the control group,and the time of anal exhaust,time of getting out of bed and eating time were earlier than those of the control group(P<0.05).The levels of hs-CRP,IL-6 and TNF-αin the experimental group were lower than those in the control group(P<0.05).The total incidence of complications in the experimental group was 6.67%,which was lower than 31.11%in the control group(P<0.05).One year after operation,the levels of hemoglobin and serum albumin in the experimental group were higher than those in the control group,and the BMI was higher than that before the operation and the number of cases was more than that in the control group(P<0.05);There was no significant difference in serum total protein levels between the two groups(P>0.05).Conclusion Compared with traditional open surgery,patients with early gastric cancer undergoing laparoscopic surgery have less trauma,less blood loss,shorter operation and hospitalization time,and fewer complications,which can help promote the recovery of the patient after surgery,and the patient's long-term health status is good.