灵枢开阖针法治疗寒湿痹阻型膝骨关节炎临床效果

Clinical effect on acupuncture of Lingshu Kaihe in the treatment of knee osteoarthritis with cold-dampness blockage pattern

目的探讨灵枢开阖针法治疗寒湿痹阻型膝骨关节炎的效果。方法选取2018年2月—2020年2月河北中医学院第一附属医院骨三科收治的寒湿痹阻型膝骨关节炎患者117例,应用计算机将其随机分为两组,其中治疗组(灵枢开阖针法治疗)59例,对照组(普通针刺治疗)58例,均连续治疗2周。分别在治疗前后记录两组的视觉模拟评分(VAS)、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)量表评分、白细胞介素-1(IL-1)和肿瘤坏死因子α(TNF-α)水平,评价两组膝关节疼痛及膝关节症状改善情况,比较两组的临床疗效。结果治疗后,两组VAS、WOMAC量表评分、IL-1、TNF-α均低于治疗前,且治疗组VAS、WOMAC量表评分均低于对照组,差异均有统计学意义(均P<0.05)。治疗后两组IL-1、TNF-α比较,差异无统计学意义(P>0.05)。治疗组临床总有效率高于对照组,差异有统计学意义(P<0.05)。结论灵枢开阖针法治疗寒湿痹阻型膝骨关节炎临床效果确切,在缓解症状方面疗效优于普通针刺治疗。

Objective To observe the efficacy on acupuncture of Lingshu Kaihe in the treatment of knee osteoarthritis with cold-dampness blockage pattern.Methods A total of 117 patients with knee osteoarthritis with cold-dampness blockage pattern admitted to the Third Department of Orthopedics,the First Affiliated Hospital of Hebei University of Chinese Medicine from February 2018 to February 2020 were selected.They were randomly divided into two groups by computer.There were 59 cases in the treatment group(acupuncture of Lingshu Kaihe),and 58 cases in the control group(ordinary acupuncture treatment),all of which were treated for two weeks.Visual analogue scale(VAS),Western Ontario and McMaster Universities osteoarthritis index(WOMAC)scale scores,interleukin-1(IL-1)and tumor necrosis factorα(TNF-α)levels were recorded before and after treatment to evaluate knee pain and improvement of knee symptoms in the two groups.The clinical efficacy of the two groups was compared.Results After treatment,VAS,the score of WOMAC scale,and the levels of IL-1 and TNF-αin both groups were lower than those before treatment,and VAS and the score of WOMAC scale in the treatment group were lower than those in the control group,with statistical significance(all P<0.05).There were no significant differences in IL-1 and TNF-αbetween the two groups after treatment(P>0.05).The total effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Acupuncture of Lingshu Kaihe has a definite clinical effect in the treatment of knee osteoarthritis with cold-dampness blockage pattern,and its effect is superior to ordinary acupuncture treatment in relieving symptoms.