Changes in newly notified cases and control of tuberculosis in China:time-series analysis of surveillance data

Background:China has made progress in tuberculosis control,but this disease remains a burden in many regions of China.We performed time-series analysis to examine changes in the rates of newly notified and newly smear-positive cases of tuberculosis in different regi ons of China from 1997 to 2018 a nd assessed the effect of the current control program.Methods:National and provincial notification data on tuberculosis from 1997 to 2018,which covers 31 provinces in the mainland of China,were extracted from the Chinese public health science data center.The annual percentage changes in newly notified and smear-positive cases were analyzed using a joinpoint regression method.