3%高渗盐水联合吸入用复方异丙托溴铵溶液雾化吸入治疗呼吸道合胞病毒肺炎的效果

Effect of 3% hypertonic saline combined with Compound Ipratropium Bromide Solution atomization inhalation in the treatment of respiratory syncytial virus pneumonia

目的探讨3%高渗盐水联合吸入用复方异丙托溴铵溶液雾化吸入治疗呼吸道合胞病毒肺炎的效果。方法选取2015年1月~2016年12月江西省宜春市人民医院收治的195例呼吸道合胞病毒肺炎患儿作为研究对象,按照随机数字表法分为治疗一组(65例)、治疗二组(65例)、治疗三组(65例)。治疗一组采用3%高渗盐水4 mL+吸入用复方异丙托溴铵溶液雾化吸入;治疗二组采用生理盐水4 mL+吸入用复方异丙托溴铵溶液雾化吸入;治疗三组采用0.9%氯化钠溶液2 mL+硫酸特布他林雾化液+布地奈德混悬液雾化吸入。比较三组患儿的咳嗽消失时间、气促消失时间、喘憋消失时间、肺部体征消失时间、住院时间及治疗效果。结果治疗一组咳嗽消失时间、气促消失时间、喘憋消失时间、肺部体征消失时间及住院时间均短于治疗二组、治疗三组,差异有统计学意义(P<0.05);但治疗二组与治疗三组的咳嗽消失时间、气促消失时间、喘憋消失时间、肺部体征消失时间及住院时间比较,差异均无统计学意义(P>0.05)。治疗一组患儿的治疗总有效率高于治疗二组、治疗三组,差异有统计学意(P<0.05);但治疗二组、治疗三组的治疗总有效率比较,差异无统计学意义(P>0.05)。结论3%高渗盐水联合吸入用复方异丙托溴铵溶液雾化吸入治疗呼吸道合胞病毒肺炎的治愈率高,能够尽快解除患儿的咳嗽、气促、喘憋、肺部体征,缩短住院时间,效果明显,值得推广。

Objective To investigate the effect of 3%hypertonic saline combined with Compound Ipratropium Bromide Solution atomization inhalation in the treatment of respiratory syncytial virus pneumonia.Methods A total of 195 children with respiratory syncytial virus pneumonia who were treated in People′s Hospital of Yichun City,Jiangxi Province from January 2015 to December 2016 were selected as the research subjects.According to the random number table method,they were divided into treatment group 1(65 cases),treatment group 2(65 cases)and treatment group 3(65 cases).The treatment group 1 received 3%hypertonic saline 4 mL+Compound Ipratropium Bromide Solution atomized inhalation.The treatment group 2 was treated with 4 mL of normal saline+Compound Ipratropium Bromide Solution atomized inhalation.The treatment group 3 was treated with 0.9%sodium chloride solution 2 mL+Terbutaline Sulfate Atomized Solution+Budesonide Suspension atomized inhalation.The time of cough disappearance,shortness of breath disappearance,asthma disappearance,lung signs disappearance,hospital stay and treatment effect of the three groups were compared.Results The disappearance time of cough,shortness of breath,dyspnea,lung signs and hospitalization time in treatment group 1 were shorter than those in treatment group 2 and treatment group 3,with statistical significances(P<0.05).However,there were no significant differences in the disappearance time of cough,shortness of breath,dyspnea,lung signs and hospitalization time between the treatment group 2 and treatment group 3(P>0.05).The total effective rate of treatment group 1 was higher than that of treatment group 2 and treatment group 3,and the difference was statistically significant(P<0.05).However,there was no significant difference in the total effective rate between the treatment group 2 and treatment group 3(P>0.05).Conclusion 3%hypertonic saline combined with Compound Ipratropium Bromide Solution atomization inhalation in the treatment of respiratory syncytial virus pneumonia has a high cure rate,which can relieve cough,shortness of breath,shortness of breath,lung signs and shorten the duration of hospitalization as soon as possible.It′s worth popularizing.