肺动脉高压患者服药依从性现状及其影响因素研究

Current status and influencing factors of medication adherence in patients with pulmonary arterial hypertension

目的了解肺动脉高压(PAH)患者服药依从性现状,探讨其服药依从性的影响因素。方法采用方便抽样法,对2019年4月8日—12月10日在北京市某三甲医院住院的226例PAH患者进行横断面调查,采用Morisky量表对PAH患者服药依从性进行评价,采用一般情况调查表、PAH知识问卷、社会支持评定量表、SAS、SDS对患者进行调查,纳入可能对PAH患者服药依从性产生影响的因素,进行单因素分析和多重逐步回归分析。结果PAH患者服药依从性评分为(5.26±0.11)分,PAH患者的疾病认知、居住地、文化程度及抑郁水平是其服药依从性的影响因素(P<0.05)。结论PAH患者服药依从性较差,在今后临床工作中要重视提高患者对疾病认知的水平,加强对患者抑郁的评估,以做到早发现、早干预,同时加强心理护理和健康宣教,提高患者服药依从性。

Objective To understand the current status of medication adherence in patients with pulmonary arterial hypertension(PAH),and to explore the influencing factors of their medication adherence.Methods From April 8 to December 10,2019,convenience sampling was used to conduct a cross-sectional survey of 226 patients with PAH hospitalized in a ClassⅢGrade A hospital in Beijing.Medication adherence of PAH patients was evaluated with the Morisky Medication Adherence Scale,and patients were investigated with the General Information Questionnaire,Pulmonary Arterial Hypertension Knowledge Questionnaire,Social Support Rating Scale,Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS).Factors that may affect the medication adherence of PAH patients were included,so as to conduct univariate analysis and multiple stepwise regression analysis.Results The medication adherence score of patients with PAH was(5.26±0.11).Disease cognition,residence,education level and depression level of PAH patients were the influencing factors of their medication adherence(P<0.05).Conclusions Patients with PAH have poor medication adherence.In the future clinical work,we should pay attention to improving patients'awareness of diseases,strengthen the evaluation of patients'depression,so as to achieve early detection and early intervention,and at the same time strengthen psychological care and health education,and improve patient compliance with medication.