多维度康复模式对军人精神分裂症患者的影响

Effect of multidimensional rehabilitation model on soldiers with schizo-phrenia

目的探索多维度康复模式对军人精神分裂症患者的影响。方法回顾性分析2015年6月—2018年6月就诊于某院的80例军人精神分裂症患者,根据患者护理方法分为观察组和对照组,对照组进行常规康复模式,观察组进行多维度康复模式,比较两组康复前以及康复后1、2年的社会功能缺陷筛选量表(SDSS)评分、家庭负担会谈量表(FIS)评分、神经生长因子(NGF)、脑源性神经营养因子(BDNF)、胰岛素样生长因子1(IGF-1)情况。结果整体分析发现:SDSS、FIS评分间比较、时间点比较及交互作用差异均有统计学意义(P<0.05)。进一步两两比较,组内比较:两组康复后1、2年SDSS、FIS评分低于同组康复前,且各组康复后2年SDSS、FIS评分低于康复后1年(P<0.05);组间比较:观察组康复后1、2年的SDSS、FIS评分低于对照组(P<0.05)。整体分析发现:IGF-1、BDNF、NGF水平组间比较、时间点比较及交互作用差异均有统计学意义(P<0.05)。进一步两两比较,组内比较:两组康复后1、2年IGF-1、BDNF、NGF水平高于同组康复前,且康复后2年IGF-1、BDNF、NGF水平高于康复后1年(P<0.05);组间比较:观察组康复后1、2年的IGF-1、BDNF、NGF水平高于对照组(P<0.05)。结论对军人精神分裂症患者实施多维度康复模式效果显著,可改善当前脑营养指标。

Objective To explore the effect of multidimensional rehabilitation model on soldiers with schizophrenia.Methods Retrospective analysis was conducted on 80 patients with schizophrenia in the military who were admitted to a hospital from June 2015 to June 2018,according to the nursing methods of patients,they were divided into observation group and control group.The control group received routine rehabilitation mode,and the observation group received multi-dimensional rehabilitation mode.Social deficiency screening scale(SDSS)scores,family burdening scale(FIS)scores,nerve growth factor(NGF),brain-derived neurotrophic factor(BDNF)and insulin-like growth factor 1(IGF-1)scores were compared between the two groups before and 1,2 years after rehabilitation.Results Overall analysis showed that there were statistically significant differences in SDSS and FIS scores,time point comparison and interaction(P<0.05).Further pair comparison,intra-group comparison:SDSS and FIS scores 1,2 years after rehabilitation in both groups were lower than before,and SDSS and FIS scores two years after rehabilitation in each group were lower than one year after rehabilitation(P<0.05).Comparison between groups:SDSS and FIS scores of observation group were lower than those of control group 1,2 years after recovery(P<0.05).Overall analysis showed that there were statistically significant differences in IGF-1,BDNF and NGF levels between groups,time point comparison and interaction(P<0.05).Further pair-to-group comparison:IGF-1,BDNF and NGF levels 1,2 years after rehabilitation in two groups were higher than before,and IGF-1,BDNF and NGF levels two years after rehabilitation were higher than one year after rehabilitation(P<0.05).Comparison between groups:The levels of IGF-1,BDNF and NGF in observation group were higher than those in control group 1,2 years after recovery(P<0.05).Conclusion The effect of multi-dimensional rehabilitation model on military schizophrenic patients is remarkable,which can improve the current brain nutrition index.