α-Synuclein在脑缺血中的作用

The Role ofα-Synuclein in Cerebral Ischemia

α-Syn(α-Synuclein,SNAC)最初是从阿尔茨海默病患者大脑的淀粉样斑块中分离出来的一种蛋白质,在突触活动中扮演着重要的角色。α-Syn主要在脑中表达,研究发现其参与脑缺血损伤发生发展。在现有证据的基础上,该文简要介绍α-Syn的基本概念,并介绍α-Syn在脑缺血后的表达变化,重点探讨α-Syn在脑缺血中的作用。该文提供的信息可能有助于对α-Syn进行深入探索,α-Syn可能是未来脑缺血诊治的有效靶点。

α-Syn(α-Synuclein,SNAC)is originally a protein isolated from the amyloid plaques in the brains of the patients,and it plays an important role in synaptic activity.α-Syn is mainly expressed in the brain.Studies have found that it is involved in the occurrence and development of cerebral ischemic injury.Based on the existing evidence,this article briefly introduces the basic concepts ofα-Syn,and then briefly introduces the expression changes ofα-Syn after cerebral ischemia,focusing on the role ofα-Syn in cerebral ischemia.The information provided in this article may help in-depth exploration ofα-Syn,which may be an effective target for the diagnosis and treatment of cerebral ischemia in the future.