小儿哮喘应用沙丁胺醇与布地奈德联合雾化的效果

Effect of Combined Nebulization of Salbutamol and Budesonide in Children With Asthma

目的分析小儿哮喘患者应用沙丁胺醇与布地奈德联合雾化吸入治疗的临床疗效及安全性。方法选取本院科室收治的小儿哮喘患者共70例,随机分组,对照组的患者采取沙丁胺醇雾化吸入治疗,观察组则在对照组的基础上增加布地奈德雾化吸入治疗。比较两组相关症状消失时间、治疗前后患者炎症以及肺部监测指标、治疗总有效率、不良反应。结果观察组相关症状消失时间、治疗后患者炎症以及肺部监测指标、治疗总有效率均优于对照组,P<0.05。两组的不良反应比较差异无统计学意义,P>0.05。结论沙丁胺醇与布地奈德雾化吸入治疗对于小儿哮喘的效果确切,可加速症状消退,控制炎症和改善肺部功能,安全性高。

Objective To analyze the clinical efficacy and safety of salbutamol and budesonide combined with aerosol inhalation in children with asthma.Methods 70 children with asthma were randomly divided into two groups.The control group was treated with salbutamol atomization inhalation,while the observation group was treated with budesonide atomization inhalation on the basis of the control group.The disappearance time of related symptoms,inflammation,lung monitoring indexes,total effective rate and adverse reactions were compared between the two groups.Results The disappearance time of related symptoms,inflammation,lung monitoring indexes and the total effective rate of treatment in the observation group were all better than those in the control group(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion Salbutamol and budesonide atomization inhalation treatment for children with asthma has a definite effect,which can accelerate the regression of symptoms,control inflammation and improve lung function,with high safety.