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胸椎旁神经阻滞对行胸腔镜肺癌根治术患者疼痛程度与应激反应的影响

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摘要 目的探究胸椎旁神经阻滞对行胸腔镜肺癌根治术患者疼痛程度及其对应激反应的影响。方法依据随机数字表法将2018年6月至2020年6月在甘肃省人民医院行胸腔镜肺癌根治术的80例患者分为对照组和观察组,各40例。对照组患者接受静脉全麻联合静脉自控镇痛,观察组患者在对照组的基础上接受胸椎旁神经阻滞。比较两组患者术后24、48 h自控镇痛情况;比较两组患者术后12、24、48 h视觉模拟疼痛量表(VAS)评分;比较两组患者术前、术后6 d应激反应;比较两组患者麻醉期间不良反应发生情况。结果观察组患者术后24、48 h自控镇痛启动次数、地佐辛输注量与对照组相比均显著减少;两组患者术后12、24、48 h的VAS评分均逐渐显著降低,且观察组显著低于对照组;术后6 d两组患者血清皮质醇(Cor)、胰岛素(INS)、去甲肾上腺素(NE)、肾上腺素(E)水平与术前相比均显著升高,但观察组显著低于对照组(均P<0.05);两组患者麻醉期间不良反应总发生率比较,差异无统计学意义(P>0.05)。结论胸椎旁神经阻滞可减轻行胸腔镜肺癌根治术患者疼痛程度,镇痛效果良好,同时可减轻应激反应,减少不良反应的发生,具有良好的临床应用安全性。
作者 胡琼花 卫毅
出处 《现代医学与健康研究电子杂志》 2021年第7期79-81,共3页 Modern Medicine and Health Research
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