摘要
糖尿病足感染是导致糖尿病足患者住院的主要原因之一。糖尿病足感染应根据临床表现诊断,并及时进行感染严重程度分级。糖尿病足创面多为慢性创面,存在多种菌感染,且菌种及抗菌药物耐药性均会随病情变化而改变。细菌生物膜也是导致抗菌药物耐药的重要原因之一。合理及时的外科治疗联合有效的抗菌药物治疗是应对糖尿病足感染挑战的有效措施。在此基础上,多学科合作会带来最佳的临床结果。
Diabetic foot infection(DFI)is one of the main causes of hospitalized patients with diabetic foot.DFI should be diagnosed according to the clinical manifestations,and the severity of infection should be graded in time.Diabetic foot wounds are mostly chronic wounds,and there are many kinds of bacterial infections.The bacteria and antibiotics resistance will change with the progress of the disease.Bacterial biofilm is also one of the important causes of antibiotic resistance.Reasonable and timely surgical treatment combined with effective antibiotic treatment is an effective measure to deal with the challenge of DFI.On this basis,multidisciplinary cooperation will achieve the best clinical outcome.
作者
徐俊
XU Jun(NHC Key Laboratory of Hormones and Development(Tianjin Medical University),Tianjin Key Laboratory of Metabolic Diseases,Department of Diabetic Foot,Tianjin Medical University Chu Hsien-I Memorial Hospital(Metabolic Diseases Hospital)&Tianjin Institute of Endocrinology,Tianjin 300134,P.R.China)
出处
《华西医学》
CAS
2021年第4期436-439,共4页
West China Medical Journal
基金
国家自然科学基金(81670766)。
关键词
糖尿病足感染
多重耐药菌
生物膜
糖尿病足骨髓炎
多学科合作
Diabetic foot infection
Multidrug-resistant bacteria
Biofilm
Diabetic foot osteomyelitis
Multidisciplinary cooperation