泮托拉唑联合中草药特色治疗胃食管反流的临床效果分析

Clinical effect of pantoprazole combined with traditional Chinese medicine in the treatment of gastroesophageal reflux

探讨泮托拉唑联合中草药特色治疗胃食管反流的临床疗效。选取2019年1月—12月门诊收治的胃食管反流患者50例,随机分为对照组和观察组各25例。对照组给予泮托拉唑钠肠溶胶囊治疗,观察组在对照组基础上联合给予中草药特色治疗,两组患者均持续治疗28 d。比较两组患者用药后的临床症状及胃镜检查食管黏膜的恢复情况,并观察患者治疗期间不良反应发生情况。两组胃食管反流患者临床症状和食管黏膜都有所改善,但观察组的有效率高于对照组(P<0.05)。两组患者治疗期间均未出现严重的不良反应。泮托拉唑联合中草药治疗胃食管反流的临床疗效确切,可改善症状和有效促进食管黏膜恢复,且安全性较高。

To investigate the clinical effect of pantoprazole combined with traditional Chinese medicine for gastroesophageal reflux.A total of 50 cases of gastroesophageal reflux selected from January 2019 to December 2019 in Aviation General Hospital were randomly divided into the control group and the observation group.The control group was given pantoprazole,and the observation group was given traditional Chinese medicine combined with pantoprazole.Both groups were treated for 28 days.The recovery of clinical symptoms,status of esophageal mucosa by endoscopy and the incidence of adverse reactions were compared between the two groups.The clinical symptoms and status of esophageal mucosa in both group were obviously improved.Efficiency of the observation group was significantly higher than that of the control group(P<0.05).No serious adverse reactions happened during treatment.Pantoprazole combined with traditional Chinese medicine has definite clinical effects in the treatment of gastroesophageal reflux,which can improve the clinical symptoms and the recovery of esophageal mucosa of patients with high safety.