斑秃相关精神心理合并症及其发病机制

Psychosomatic Aspects of Alopecia Areata:Pathogenesis and Complications

斑秃是一种突然发生的、非瘢痕性脱发,目前认为斑秃的发生与遗传因素、精神因素、免疫紊乱、内分泌失调、微循环障碍等因素有关。斑秃相关的精神心理方面包括原发的精神心理压力导致斑秃发生,以及继发于斑秃的精神疾病如抑郁症、焦虑症等。精神压力可以是斑秃的主要病因或加重诱因,也可以是斑秃的继发性改变。本文着重介绍精神因素诱发斑秃的机制及斑秃相关心身疾病。

Alopecia areata(AA)is a kind of non-scarring hair loss that appears suddenly.It is believed that the occurrence of AA is related to genetic factors,mental factors,immunologic derangement,endocrine dyscrasia and microcirculation disorders.The psychosocial aspects of AA include primary and secondary perspectives.The primary mental stress leads to the occurrence of AA,and secondary condition such as depression and anxiety can be caused by psycho-emotional stress results from hair loss.Psycho-emotional stress could be a major etiology or an aggravating factor for AA,but also secondary problems in response to hair loss.This paper mainly introduces the mental factors in the pathogenesis and psychosomatic disorders of AA.