首发急性脑卒中患者发病部位与3年内卒中后抑郁发病的相关性分析

Correlation analysis of post-stroke depression in patients with first acute stroke within 3 years

目的探讨首发急性脑卒中患者不同发病部位对病后较长时期卒中后抑郁发病的相关性分析。方法选取2016-03—2017-05于新乡医学院第三附属医院首次确诊的148例脑卒中患者为研究对象,经治疗离院后持续随访时间>3 a,收集患者的人口学资料、影像学资料和出院后的运动功能、精神状态检查结果,观察术后3年内抑郁的发病情况和影响因素,并对相关因素与抑郁水平的相关性进行分析。结果 148例脑卒中患者随访3 a期间共发生卒中后抑郁(PSD)80例,占54.05%。组间比较显示,PSD患者和非PSD患者在性别、卒中偏侧、NIHSS评分、FMA评分、手功能及步行功能方面差异有统计学意义(P<0.05)。Spearman相关性分析显示,抑郁自评量表(SDS)评分与偏侧性无相关性(P>0.05),与FMA评分、手功能及步行功能均呈负相关(P<0.05)。结论脑卒中偏侧性与PSD发生无关,而运动功能恢复不佳与PSD发生密切相关。

Objective To investigate the effects of different sites of onset on the onset of post-stroke depression in patients with first acute stroke.Method A total of 148 cases of cerebral apoplexy patients in our hospital for the first time confirmed from March 2016 to May 2017 as the research objects were selected.After treatment of departure from the hospital last time>3 years follow-up,the patient’ s demographic information,the movement of image information and the test results of function and mental state after discharge were collected.The incidence and the influence factors of depression after three years was observed,and the related factors correlated with the level of depression was analyzed.Results There were 80 cases(54.05%) of patients occurred PSD in 148 stroke patients during 3-year follow-up.Comparison between groups showed that there were statistically significant differences between PSD patients and non-PSD patients in gender,stroke side,NIHSS score,FMA score,hand function and walking function(P<0.05).Spearman correlation analysis showed that SDS score was not correlated with laterality(P>0.05),but was negatively correlated with FMA score,hand function and walking function(P<0.05).Conclusion Cerebral apoplexy had no correlation with PSD,but poor motor function recovery has close correlation with PSD.