蚕丝蛋白微球和微囊的制备及其应用研究进展

Research Progress on Preparation and Application of Silk Protein Microspheres and Microcapsules

近年来,为拓展蚕丝在生物医药、化妆品、食品和光电材料等领域的应用,人们通过交联、修饰和接枝等理化方法对蚕丝进行改性处理研究,采用不同的制备方法获得粒径为几十纳米到几百微米不等的蚕丝蛋白材料,并研究其物理、化学和生物特性,以发现其特有的功能。结合近年来国内外蚕丝蛋白微球/微囊制备技术的研究成果,综述了蚕丝蛋白微球/微囊的制备方法,归纳了蚕丝蛋白微球/微囊的类型及影响蚕丝蛋白微球/微囊粒径尺寸、形状结构和性能的因素,介绍了蚕丝蛋白微球/微囊的最新应用研究。

In order to expand application of silk in the fields of biomedicine,cosmetics,food and optoelectronic materials,it has been modified by crosslinking,modifying and grafting in recent years.Silk protein materials with different sizes from tens of nanometers to hundreds of micrometers were obtained by different methods,and their physical,chemical and biological properties were studied to find its unique characteristics.In this study,different ways to prepare silk protein microspheres/microcapsules were reviewed,types of silk protein microspheres/microcapsules and factors affecting its particle size,shape,structure and performance were summarized,and the latest application research on silk protein microspheres/microcapsules was also introduced based on recent research on silk protein microspheres/microcapsules at home and abroad.