简化认知行为治疗对轻中度抑郁障碍患者压力知觉的疗效研究

The Efficacy of Simplified Cognitive Behavior Therapy for Stress Perception in Patients with Mild to Moderate Depressive Disorder

目的:探讨简化认知行为治疗对轻中度抑郁障碍患者压力知觉的影响,为相关研究提供参考。方法:纳入符合ICD-10中轻、中度抑郁发作标准的被试,根据随机原则分为对照组(药物+支持心理组)和干预组(药物+简化认知行为组),采用盲法评估,于干预前后各进行一次17项汉密顿抑郁量表(HAMD-17)、汉密尔顿焦虑量表(HAMA)和中文版压力知觉量表(CPSS)的测定,以评价干预效果。结果:完成8周干预65例患者(对照组33例,干预组32例)。两组在人口学资料差异无统计学意义(P>0.05);基线评估时,两组在抑郁、焦虑和压力知觉得分差异无统计学意义(P>0.05);8周末,两组在抑郁、焦虑和压力知觉得分差异有统计学意义(P<0.05),干预组得分均低于对照组。组内比较结果显示,对照组、干预组的抑郁、焦虑、压力知觉评分在治疗前后差异均有统计学意义(P<0.05)。结论:药物+支持性心理治疗和药物+简化认知行为治疗2种干预方式均有助于改善轻中度抑郁障碍患者的压力知觉,药物+简化认知行为治疗方式的干预效果优于药物+支持下心理治疗方式。

Objective:To investigate the efficacy of simplified cognitive behavior therapy(SCBT)for stress perception in patients with mild to moderate depressive disorder,to provide reference for related research.Methods:Patients with mild to moderate depressive episodes of ICD-10 were enrolled.They were randomly divided into the control group(drug+supportive psychotherapy,control group)and the intervention group(drug+simplified cognitive behavior therapy,SCBT group).The 17-item Hamilton Depression Scale(HAMD-17),Hamilton Anxiety Scale(HAMA)and Chinese Perceived Stress Scale(CPSS)were measured before and after the intervention.Results:The intervention lasted 8 weeks,65 patients were enrolled(33 control group,32 SCBT group).There was no significant difference in demographic data between the two groups(P>0.05).At baseline assessment,there was no significant difference in depression,anxiety and stress perception scores between the two groups(P>0.05).At the eighth weekend,the depression,anxiety and stress cognitive scores between the two groups were significantly different(P<0.05).The scores of the intervention group were lower than those of the control group.The comparison results within the groups showed that the differences in depression,anxiety and stress perception scores between the control group and the intervention group before and after treatment were significant(P<0.05).Conclusion:Both groups are helpful to improve the stress perception of patients with mild to moderate depressive disorder.Simplified cognitive-behavioral therapy is better than routine care.