肝细胞癌非手术治疗的发展现状

Current developmental status of non-surgical treatment of hepatocellular carcinoma

肝细胞癌是临床上常见且死亡率较高的恶性肿瘤之一。随着影像及介入技术的进步,经肝动脉化疗栓塞术、局部消融治疗等应用日益广泛,在某些早期肝细胞癌的治疗中甚至能达到与手术相同的效果。精准医学和生物医学也得到蓬勃发展,放化疗被更准确、有效的应用于肝细胞癌的治疗中,分子靶向治疗、免疫治疗、基因治疗等成为未来的突破方向。就肝细胞癌非手术治疗的最新进展进行综述。

Hepatocellular carcinoma(HCC)is one of the most common malignant tumors with high mortality in clinical practice.With the development of imaging and interventional techniques,transcatheter arterial chemoembolization and local ablation are more and more widely used for treatment and can even achieve a similar effect as surgery in the treatment of some types of early-stage HCC.In addition,precision medicine and biomedicine have also developed vigorously;radiochemotherapy is more accurate and effective in the treatment of HCC,and molecular targeted therapy,immunotherapy,and gene therapy have become the directions for breakthrough in the future.This article reviews the latest advances in the non-surgical treatment of HCC.