脑卒中后抑郁的病因及发病机制研究进展

Developments on the etiology and pathogenesis of post-stroke depression

抑郁症是缺血性卒中最常见的并发症,对存活者的功能恢复和生活质量产生很大的负面影响。约1/3的人受到卒中后抑郁的影响,这使其成为一个严重的社会和公共卫生问题。合理预防及治疗卒中后抑郁需要对此疾病的病理生理因素有一个综合的认识。对脑卒中后抑郁的病因及发病机制进行详细综述可为以后此疾病的预防及治疗提供更全面、更系统的科学依据。

Depression is the most common complication of ischemic stroke,which has a great negative impact on the functional recovery and quality of life of survivors.About 1/3 people are affected by post-stroke depression,which makes it a serious social and public health problem.Reasonable prevention and treatment of post-stroke depression requires a comprehensive understanding of the pathophysiological factors of the disease.A detailed review of the etiology and pathogenesis of post-stroke depression can provide a more comprehensive and systematic scientific basis for the prevention and treatment of this disease in the future.