Sysmex XN-1000血细胞分析仪血小板聚集报警信息分析

Analysis of platelet aggregation alarm information with Sysmex XN-1000 blood cell analyzer

目的分析Sysmex XN-1000全自动血细胞分析仪(以下简称XN-1000)血小板聚集报警信息的符合性,并探讨其处理方法。方法住院患者XN-1000血小板聚集报警值>100的123例为高值组,随机对应抽取年龄、性别、血小板数值相仿且血小板聚集报警值0~100的123例为低值组。并分别制作血涂片人工镜检血小板聚集情况和手工血小板计数。结果高值组人工镜检血小板聚集阳性53例、阴性70例,低值组人工镜检血小板聚集阳性1例,阴性122例,血小板聚集报警的敏感性为98.15%,特异性为63.54%,阳性预测值为43.09%,阴性预测值为99.19%,准确性为71.14%。结论XN-1000血小板聚集报警信息可以很好筛选出血小板聚集,不易漏诊,但聚集准确性须人工镜检进一步核实。

Objective To analyze the coincidence of platelet aggregation alarm information of Sysmex XN-1000 blood cell analyzer(hereafter referred to as XN-1000)and explore its treatment method.Methods A total of 123 inpatients with platelet aggregation alarm value>100 in whole blood cell analysis were collected,which were the high value group.123 cases with similar platelet values of age and gender and alarm value of platelet aggregation 0-100 were randomly selected as the low value group.Blood smear was used to determine platelet aggregation and manual platelet count.Results In the high value group,there were 53 positive and 70 negative cases of platelet aggregation,while in the low value group,there were 1 positive and 122 negative cases.The sensitivity,specificity,positive predictive value,negative predictive value and accuracy of platelet aggregation alarm were 98.15%,63.54%,43.09%,99.19%and 71.14%,respectively.Conclusion XN-1000 platelet aggregation alarm information can well screen out platelet aggregation and is not easy to miss diagnosis,but it's accuracy needs to be further verified by manual microscopic examination.