摘要
人脑是自然界生物体内结构和功能最复杂的器官。解析人类基因组如何编码人脑的结构与功能是极具挑战的科学与技术问题,也是从根本上认识脑的本质问题。本文对近年来脑的“断面”组学研究的相关进展进行归纳,提出解析基因组如何编码脑的挑战与展望。
Human brain is the most complicated living organ in nature.How the human genome encodes the structure and function of brain is a fundamental question to understand the essence of mind.Currently,it is still an unsolved scientific problem requiring the further breakthrough of comprehensive technologies.Here,we summarize the recent advances in brain development/function OMICS studies,and discuss the huge challenges and prospects in understanding how brain is encoded by genome.
作者
谢维
林承棋
李健
李默怡
Wei Xie;Chengqi Lin;Jian Li;Moyi Li(The Key Laboratory of Developmental Genes and Human Disease,School of Life Science and Technology,Southeast University,Nanjing 210096,China;Department of Genetics and Development,School of Medicine,Southeast University,Nanjing 210009,China;Institute for Brain and Intelligence,Southeast University,Nanjing 210096,China)
出处
《遗传》
CAS
CSCD
北大核心
2021年第5期393-396,共4页
Hereditas（Beijing)
基金
国家自然科学基金项目(编号:91632201,31430035)资助。
关键词
脑
发育
基因组
编码
自闭症
brain
development
genome
encode
autism
