安脱达屋尘螨变应原疫苗与低温等离子治疗变应性鼻炎的疗效比较

Comparison of the Curative Effect of Alutard House Dust Mite Allergens Vaccine and Low-temperature Plasma in the Treatment of Allergic Rhinitis

目的:对比分析安脱达屋尘螨变应原疫苗与低温等离子分别治疗变应性鼻炎(allergic rhinitis,AR)的疗效。方法:选取我院2018年1月至2019年12月收治的88例变应性鼻炎患者作为研究对象,按随机分组方法,分成研究组和常规组两组,每组患者各44例。其中常规组患者予以低温等离子治疗;研究组患者予以安脱达屋尘螨变应原疫苗注射治疗。治疗12个月后,对比分析两组患者的临床治疗效果。结果:研究组患者临床疗效(93.18%)高于常规组患者临床疗效(79.55%)(P<0.05);治疗前,两组患者的临床症状评分差异无统计学意义(P>0.05);治疗后,研究组与常规组临床症状评分均降低,且研究组降低幅度更大(P<0.05);研究组患者不良反应总发生率6.82%,低于常规组不良反应总发生率(27.27%)(P<0.05)。结论:相比于低温等离子治疗变应性鼻炎的临床效果,安脱达屋尘螨变应原疫苗注射治疗变应性鼻炎患者所获得的临床疗效更佳,可以减轻患者临床症状,且不良反应少,安全性较高。

Objective:To compare and analyze the efficacy of alutard house dust mite allergens vaccine and low-temperature plasma in the treatment of allergic rhinitis.Methods:88 patients with allergic rhinitis admitted in our hospital from January 2018 to December 2019 were selected as the research objects.According to the computer randomization method,they were divided into two groups:the study group and the routine group,with 44 patients in each group.Patients in the routine group were treated with low-temperature plasma treatment,and patients in the study group were treated with alutard house dust mite allergens vaccine injection.The clinical treatment effects of the two groups of patients were compared and analyzed.Results:The clinical efficacy of patients in the study group(93.18%)was higher than that of the routine group(79.55%)(P<0.05).Before treatment,there was no significant difference in clinical symptom scores between the two groups(P>0.05).After treatment,the clinical symptom scores of both two groups reduced.And the reduction in the study group was more obvious(P<0.05).The total incidence of adverse reactions in the study group was 6.82%,which was lower than that in the routine group(27.27%)(P<0.05).Conclusion:Compared with low-temperature plasma treatment of allergic rhinitis,alutard house dust mite allergens vaccine injection has better clinical effect in the treatment of allergic rhinitis,which can alleviate the clinical symptoms of patients,and has fewer adverse reactions and higher safety.