探讨卡前列素氨丁三醇应用于高危妊娠产后出血的效果

Exploration on the Effect of Carprost Tromethamine Applied in High-Risk Pregnancy postpartum hemorrhage

目的探讨高危妊娠临床产妇予以卡前列素氨丁三醇的实际效果及其对产后出血的影响。方法方便选取就诊区间2018年1月—2020年6月该院诊治的98例高危妊娠产妇予以研究,依据数字随机抽取法划分对照组(49例,予常规治疗)、观察组(49例,予卡前列素氨丁三醇治疗),就二者间出血量、血红蛋白水平以及不良反应率展开对比。结果两组分娩前血红蛋白水平对比,差异无统计学意义(t=0.054,P>0.05);两组分娩后24 h血红蛋白水平均明显降低但观察组优于对照组,观察组血红蛋白水平为(91.29±8.76)g/L,对照组为(84.65±9.15)g/L,差异有统计学意义(t=3.669,P<0.05)。观察组术中出血量(175.29±30.12)mL,产后2 h出血量(137.17±27.39)mL,产后24 h出血量(204.68±32.11)mL,明显优于对照组的(263.21±35.68)mL,(207.38±34.09)mL,(313.55±39.57)mL,差异有统计学意义(t=13.180、11.239、14.955,P<0.05);观察组不良反应率4.08%低于对照组的20.41%,差异有统计学意义(χ^(2)=6.078,P<0.05)。结论针对高危妊娠产妇应用卡前列素氨丁三醇治疗可取得理想效果,妊娠剖宫产围术期出血量较少,不良发应率更低。

Objective To investigate the actual effect of carboprost tromethamine and its effect on postpartum hemorrhage in high-risk pregnancy clinical parturients.Methods convenient select the trectment interval from January 2018 to June 2020,98 high-hisk pregnicant uomen diaynosed and treated in the hospital for research.The control group(49 cases received conventional treatment)and the observation group(49 cases received carprost tromethamine treatment),to compare the bleeding volume,hemoglobin level and adverse reaction rate between the two groups.Results There was no statistically significant difference in the hemoglobin level of the two components before delivery(t=0.054,P>0.05);the hemoglobin level of the two components at 24 h after delivery was significantly reduced,but the observation group was better than the control group,the observation group’s hemoglobin level was(91.29±8.76)g/L,the control group was(84.65±9.15)g/L,the difference was statistically significant(t=3.669,P<0.05).The intraoperative blood loss of the observation group was(175.29±30.12)mL,the blood loss 2 h postpartum(137.17±27.39)mL,and the blood loss 24 h postpartum(204.68±32.11)mL were significantly better than the control group(263.21±35.68)mL,(207.38±34.09)mL,(313.55±39.57)mL,the difference was statistically significant(t=13.180,11.239,14.955,P<0.05);the adverse reaction rate of the observation group was 4.08%lower than that of the control group 20.41%,the difference was statistically significant(χ^(2)=6.078,P<0.05).Conclusion The application of carboprost tromethamine treatment for high-risk pregnant women can achieve ideal results.The perioperative bleeding of pregnancy cesarean section is less,and the rate of adverse reactions is lower.