ctDNA进行微小残留病灶监测和疾病复发预测

Monitoring of Minimal Residual Disease And Prediction of Disease Recurrence by ctDNA

1文献来源Chen K,Zhao H,Shi Y,et al.Perioperative dynamic changes in circulating tumor DNA in patients with lung cancer(DYNAMIC)[J].Clin Cancer Res,2019,25(23):7058-7067.2证据水平1b。3背景既往研究表明,循环肿瘤DNA(circulating tumor DNA,ctDNA)水平反映了全身性肿瘤总负担。完全手术后,ctDNA水平应降低,并且随着肿瘤复发而升高。