不同年龄支原体肺炎患儿的临床特征及相关指标的关联性研究

Study on the correlation between clinical characteristics and related indexes of children with mycoplasma pneumonia of different ages

目的对不同年龄支原体肺炎患儿的临床特征及相关指标进行分析比较,以期为临床诊疗及疾病判断提供理论依据。方法对120例我院儿科住院患儿的病案资料进行回顾性分析。结果婴幼儿组喘息更多见,年长儿组单纯性咳嗽较多见,婴幼儿组以小叶性肺炎多见,年长儿组以大叶性肺炎多见,2组比较差异有统计学意义(P<0.05)。不同抗体滴度水平下,2组患儿的C反应蛋白(CRP)、乳酸脱氢酶(LDH)、D二聚体(Ddimer,DD)、红细胞沉降率(erythrocyte sedimentation rate,ESR)指标比较差异均有统计学意义(P<0.05);同一抗体滴度水平下,2组患儿的白细胞计数(white blood cell,WBC)、中性粒细胞比例(proportion of neutrophils,N%)、LDH指标比较差异有统计学意义(P<0.05)。2组患儿血清CRP、LDH、DD与ESR水平两两之间呈正相关关系(P<0.05)。结论在支原体肺炎中,婴幼儿与年长儿的临床症状、影像学表现、实验室检查等方面均有差异。在治疗的同时,应综合年龄来判断病原,积极有针对性的治疗,有助于促进病情恢复,缩短病程,减少并发症的发生。

Objective To analyze and compare the clinical characteristics and related indicators of children with mycoplasma pneumonia of different ages,so as to provide theoretical basis for clinical diagnosis and treatment and disease judgment.Methods The medical records of 120 children in our hospital were analyzed retrospectively.Results Wheezing was more common in the infant group,simple cough was more common in the elder group.Lobular pneumonia was more common in infant group and lobar pneumonia was more common in elder group.The differ-ence was statistically significant(P<0.05).At different antibody titer levels,CRP,LDH,DD and ESR were all statistically significant between the two groups(P<0.05).At the same antibody level,WBC,N%and LDH indexes of the two groups were statistically significant(P<0.05).There was a positive correlation between the levels of CRP,LDH,DD and ESR(P<0.05).Conclusion In Mycoplasma pneumoniae pneumonia,there are differences in clinical symptoms,imaging manifestations and laboratory tests between infants and elder children.At the same time of treatment,we should judge the pathogen according to the age,and take active and targeted treatment,which is helpful to promote the recovery of the disease,shorten the course of disease and reduce the complications.