红外光谱法研究再生丝素蛋白薄膜的构象转变

Study on Conformational Transition of Regenerated Silk Fibroin Films by Infrared Spectroscopy

通过流延法制备的再生丝素蛋白薄膜具有高透光率和可控的降解速率,是制造柔性透明电子器件的理想基底材料。但再生丝素蛋白薄膜的结构和性质通常受溶液性质的影响。在此,本文使用高温高压法从蚕茧中提取丝素蛋白,并通过流延法制备了再生丝素蛋白及其复合膜。结合红外光谱以及傅立叶自解卷积的方法分析发现,碱性物质能够有效削弱高温和糖类化合物对丝素蛋白构象转变的促进作用。

The regenerated silk fibroin film prepared by casting method has high light transmittance and controllable degradation rate,which is an ideal substrate material for manufacturing flexible and transparent electronic devices.However,the structure and properties of regenerated silk fibroin films are usually affected by properties of solution.Here,silk fibroin was extracted from silkworm cocoons by the high temperature and high-pressure method,and the regenerated silk fibroin and its composite film were prepared by casting method.The effects of alkaline substances and carbohydrate compounds on the secondary structure of regenerated silk fibroin films were analyzed by infrared spectroscopy.